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[Experts consensus statement on Qilong Capsules in clinical practice].

Zhi-Fei Wang1, Ying-Zhen Xie2, Yan-Ming Xie1

  • 1Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences Beijing 100700,China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
|April 3, 2020
PubMed
Summary

Qilong Capsules, a traditional Chinese medicine for ischemic stroke, require specific usage guidelines. This consensus provides evidence-based recommendations for optimal efficacy and safety in treating cerebral infarction.

Keywords:
Qilong Capsulesclassification of evidenceclinical practiceexpert consensus statementrecommendation

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Area of Science:

  • Traditional Chinese Medicine (TCM)
  • Neurology
  • Pharmacology

Background:

  • Qilong Capsules are a key TCM formulation for invigorating Qi and activating blood circulation.
  • Ischemic stroke (cerebral infarction) is a complex condition with varied treatment needs across different stages.
  • Current clinical application of Qilong Capsules faces challenges regarding timing, dosage, and treatment duration, potentially leading to suboptimal efficacy and adverse events like bleeding.

Purpose of the Study:

  • To develop a consensus on the rational clinical application of Qilong Capsules for ischemic stroke.
  • To provide evidence-based recommendations and expert consensus suggestions for optimizing Qilong Capsules' use.
  • To guide healthcare professionals in the appropriate use of Qilong Capsules in managing cerebral infarction.

Main Methods:

  • Convened a multidisciplinary expert panel including TCM clinicians, pharmaceutical experts, and evidence-based medicine methodologists.
  • Synthesized existing clinical research evidence and incorporated expert clinical experience.
  • Developed recommendations addressing indications, timing, dosage, treatment course, combination therapy, and contraindications.

Main Results:

  • The consensus outlines specific recommendations for Qilong Capsules in treating ischemic stroke.
  • Guidance is provided on appropriate intervention timing, dosage, and duration of treatment.
  • Safety characteristics and contraindications are detailed to minimize adverse reactions, such as bleeding.

Conclusions:

  • Rational use of Qilong Capsules requires adherence to evidence-based guidelines and expert consensus.
  • The consensus aims to improve the efficacy and safety of Qilong Capsules in ischemic stroke management.
  • This guidance supports healthcare professionals in making informed decisions for patients with cerebral infarction.