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[Predictors of kidney function in a cohortof Mexican adults]
Elva L Torrescano-de Labra1, Lea A Cupul-Uicab2, Paula Ramírez-Palacios3
1Escuela de Salud Pública de México, Instituto Nacional de Salud Pública. Cuernavaca, Morelos, México.
Objective:
Our aim was to examine prospectively predictors of subclinical renal alterations among adults without chronic kidney disease.
Materials And Methods:
We analyzed data from a cohort of Mexican adults (n=757). Kidney function (2010) was assessed with the estimated glomerular filtration rate (eGFR-Cr), serum creatinine and uric acid. Predictors of each kidney function marker (2004) were identified with linear and logistic regression models.
Results:
33% had an eGFR-Cr 40 years old and users of antihypertensive medication; and higher among those with a high protein intake. Serum creatinine predictors were similar to those observed for eGFR-Cr. Uric acid decreased in men, among those with obesity, hypertension and high cholesterol.
Conclusions:
Conventional kidney function biomarkers are useful to identify subclinical alterations. Some predictors of kidney function are potentially modifiable, therefore susceptible for intervention among high-risk groups.
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