Local fat content and muscle quality measured by a new electrical impedance myography device: correlations with ultrasound variables

AbstractThe present study investigated the relationship between local fat percentage (SK_fat) and muscle quality (MQ) estimated by a new hand-held electrical impedance myography (hEIM) device or derived from ultrasound and strength assessments. The right anterior thigh of 90 healthy participants (mean ± SD; age=22.9 ± 2.9 years; 45 men: BMI = 23.9 ± 2.4 kgm^-2; 45 women: BMI = 21.1 ± 1.9 kgm^-2) was scanned by hEIM and ultrasound. Correlations between SK_fat, local subcutaneous fat (SUB_fat), and echo intensity (EI_us) were explored. Correlations between MQ, EI_us, quadriceps femoris anatomical cross-sectional area (ACSA_QF), knee extensors maximum voluntary isometric torque (T), T/ACSA_QF, EI_us/SUB_fat, and ACSA_QF/SUB_fat were also assessed. SK_fat correlated with SUB_fat (r = 0.88; p < 0.001) and EI_us (r = 0.64; p < 0.001). MQ correlated with EI_us (r = -0.66; p < 0.001), ACSA_QF (r = 0.37; p < 0.001), EI_us/SUB_fat (r = 0.37; p < 0.001), and ACSA_QF/SUB_fat (r = 0.81; p < 0.001). Multiple regression analysis showed that SUB_fat, EI_us, and sex explained 86% of SK_fat variance, whereas ACSA_QF/SUB_fat, sex and EI_us explained 75% of MQ variance. In conclusion, high hEIM local fat percentage relates to greater subcutaneous fat and intramuscular non-contractile tissue content. High hEIM muscle quality relates to greater muscle-size:subcutaneous-fat ratio and contractile tissue content. Sex influences the prediction of both parameters. This hEIM device seems to be useful to estimate local thigh composition.