Highly sensitive and selective optosensing of quercetin based on novel complexation with yttrium ions

A simple and fast method was developed for the determination of quercetin. The concentration of quercetin can be determined based on the fluorescence emission resulting from the coordinative interactions between quercetin and the yttrium ion (Y³⁺). Notably, a portable platform to quantitatively analyze quercetin was constructed. This platform incorporates our custom-built homemade reader based on a photodiode, and Arduino hardware, which accepts a paper ribbon on which Y³⁺ is deposited as an input. In addition, the color change of the paper ribbon was identified using a smartphone via the hue values of the photographs. The limits of detection for quercetin using spectroscopy, a smartphone, and a custom-built reader were calculated to be 27, 110, and 129 nM, respectively. The use of a custom-built device and a smartphone for detecting quercetin via fluorescence from the prepared paper ribbon reduces the time and cost of quercetin detection. This approach could be employed for on-site sensing of quercetin in real samples.