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Vaccination coverage of children with chronic diseases is inadequate especially for specifically recommended vaccines
Diariatou Diallo1, Claire Santal1, Marion Lagrée1
1Paediatric Emergency Unit & Infectious Diseases, CHU Lille, Lille, France.
Insights
Vaccine coverage is low and delays are common in children with chronic diseases, highlighting a need for improved adherence to recommended and specialized vaccines.
Area of Science:
- Pediatric Health
- Immunization Science
- Public Health
Background:
- Children with chronic diseases often have unique vaccination needs.
- Inadequate vaccination can lead to increased risk of preventable diseases in vulnerable populations.
Purpose of the Study:
- To assess vaccine coverage and identify delays in generally recommended vaccines for children with chronic diseases.
- To determine factors associated with under-vaccination for vaccines specifically recommended for chronic conditions.
Main Methods:
- Point-prevalence surveys conducted in pediatric units.
- Analysis of vaccination data for children aged 2 months to 18 years with chronic conditions.
- Multivariable analysis to identify factors associated with under-vaccination.
Main Results:
- Only 47% of children with chronic diseases were up-to-date on general vaccinations.
- Significant delays (26%-75%) were observed for recommended vaccines.
- Low maternal education was linked to under-vaccination (aOR=10.5, P=.03).
Conclusions:
- Children with chronic diseases exhibit insufficient vaccine coverage and substantial vaccination delays.
- Targeted interventions are needed to improve adherence to vaccination schedules in this population.
Aim:
Our objectives were to measure the vaccine coverage rates for children with chronic diseases as well as the prevalence of potentially harmful delays for generally recommended vaccines. We also identified the factors influencing non-adherence to vaccines specifically recommended for chronic conditions.
Methods:
Three non-interventional point-prevalence surveys were performed in 2014 in all paediatric units at Lille University Hospital among children aged 2 months-18 years with chronic diseases and vaccination data. Vaccine coverage and delays for generally recommended vaccines were studied. The children who were up-to-date and those under-vaccinated for specifically indicated vaccines were compared and the factors potentially associated with under-vaccination were studied with multivariable analysis.
Results:
We screened 682 patients: of 207 with chronic diseases, mainly neurological, muscular and respiratory disorders, 146 had vaccination data. Only 47% (95% confidence interval 39-55) were up-to-date for all generally recommended vaccinations; potentially harmful vaccination delays were high (26%-75%). Only 11% of the 81% of patients for whom some vaccines were specifically recommended were up-to-date. Low maternal education level was significantly associated with under-vaccination (adjusted odds ratio 10.5, 95% confidence interval 1.3-86.9, P = .03).
Conclusion:
This study showed inadequate vaccine coverage rates and significant delays among children with chronic diseases.
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