Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hypothesis: Accept or Fail to Reject?

Hypothesis: Accept or Fail to Reject?

The outcome of any hypothesis testing leads to rejecting or not rejecting the null hypothesis. This decision is taken based on the analysis of the data, an appropriate test statistic, an appropriate confidence level, the critical values, and P-values. However, when the evidence suggests that the null hypothesis cannot be rejected, is it right to say, 'Accept' the null hypothesis?
There are two ways to indicate that the null hypothesis is not rejected. 'Accept' the null...

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...

Predicting Reaction Outcomes

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...

Strategies for Assessing and Addressing Confounding

Strategies for Assessing and Addressing Confounding

Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Population Genetics Reveals Insights Into <i>Cryophytum</i> Biogeography in South Africa.

Ecology and evolution·2026

Same author

Population Genetics Reveals the Invasion Pathways of <i>Mesembryanthemum nodiflorum</i> in North America.

Ecology and evolution·2025

Same author

Impact of intraspecific variation in insect microbiomes on host phenotype and evolution.

The ISME journal·2023

Same author

Uncovering the phylogeography of <i>Schinus terebinthifolia</i> in South Africa to guide biological control.

AoB PLANTS·2022

Same author

Evolution of growth traits in invasive Pereskia aculeata (Cactaceae): testing the EICA hypothesis using its specialist herbivore, Catorhintha schaffneri (Coreidae).

Pest management science·2020

Same author

Global Actions for Managing Cactus Invasions.

Plants (Basel, Switzerland)·2019

Same journal

Endocrine modulation of macronutrient self‑selection in feeding behavior.

Current opinion in insect science·2026

Same journal

To Repel the Red Imported Fire Ant: A Review of Progress, Limitations, and Prospects.

Current opinion in insect science·2026

Same journal

The Growing Challenge of Varroa destructor Resistance to Acaricides: Seeking Sustainable Solutions.

Current opinion in insect science·2026

Same journal

Regulation of beneficial intracellular symbionts in insects.

Current opinion in insect science·2026

Same journal

Insecticide Resistance in Indonesia: Status, Challenges, and Way Forward in Management of Agricultural Pests.

Current opinion in insect science·2026

Same journal

Toward adaptive and high‑precision Integrated Pest Management in the big data era.

Current opinion in insect science·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 25, 2025

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

Predicting non-target impacts.

Quentin Paynter¹, Iain D Paterson², Raelene M Kwong³

¹Manaaki Whenua - Landcare Research, Private Bag 92170, Auckland, New Zealand.

Current Opinion in Insect Science

|April 3, 2020

Summary

This summary is machine-generated.

Biocontrol agents offer benefits for invasive weed management but face challenges due to non-target impacts. Refined host-range testing and understanding indirect effects are crucial for effective and safe biocontrol implementation.

More Related Videos

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox

Published on: August 28, 2019

Related Experiment Videos

Last Updated: Dec 25, 2025

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox

Published on: August 28, 2019

Area of Science:

Ecology
Environmental Science
Biological Control

Background:

Biocontrol of invasive alien weeds provides significant ecological and economic benefits.
Concerns regarding non-target impacts on native flora and indirect ecological interactions hinder biocontrol adoption in some regions.

Purpose of the Study:

To address uncertainties in predicting the host range of biocontrol agents.
To highlight the need for refined host-range testing protocols.
To explore the complexities of indirect non-target impacts and their temporal dynamics.

Main Methods:

Review of current biocontrol implementation challenges.
Analysis of host-range testing limitations.
Discussion of indirect interactions and evolving risks.

Main Results:

Current host-range testing may overestimate risks, leading to the erroneous rejection of potential biocontrol agents.
Indirect non-target impacts are difficult to predict and can change over time.
Climate change may alter the risk profiles of biocontrol agents and their impacts.

Conclusions:

Refining host-range testing protocols is essential for accurate risk assessment in biocontrol.
Further research is needed to understand and predict long-term non-target impacts, including those influenced by climate change.
Addressing uncertainties in host-range prediction and indirect effects will improve the successful implementation of biocontrol strategies.