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Autophagy efficacy and vitamin D status: Population effects

Abhimanyu1, Vanessa Meyer1, Brandon R Jones1

  • 1Department of Biochemistry, University of Johannesburg, Auckland Park Kingsway Campus, PO Box 524, Auckland Park 2006, Gauteng, South Africa.

Cellular Immunology
|April 4, 2020
PubMed
Summary

Vitamin D receptor (VDR) signaling influences autophagy differently across populations. Supplementation with 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) can enhance autophagy, particularly in vitamin D deficient individuals.

Keywords:
AfricanAutophagyBeclin1LC3-IIBPam(3)CSK(4)Population-specificTLR2/1VDRVitamin D

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