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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
[Ocular manifestations of measles in adults: About three cases]
E Issam Eddine1, S Sana1, F Achraf1
1Service d'ophtalmologie, hôpital Mohamed-Taher-Maamouri, Mrazka, 8000 Nabeul, Tunisie.
Abstract:
Measles is a contagious viral infection that usually affects children. The disease is caused by morbillivirus, a virus of the family Paramyxoviridae. The clinical picture is characterized by four phases: incubation, invasion, eruption and desquamation. Ophthalmologic manifestations in measles are rare, dominated by conjunctivitis and keratitis. Corneal involvement is the main concern; it varies from simple superficial punctate keratitis to corneal perforation. We report three cases of acute keratitis in young adults during an epidemic. The epithelial involvement was peripheral, central or diffuse. The outcome was favorable under symptomatic topical treatment.
Insights
Measles can cause rare but serious eye complications like keratitis, even in adults. Prompt symptomatic treatment led to favorable outcomes in three young adults during a measles epidemic.
Area of Science:
- Ophthalmology
- Virology
- Infectious Diseases
Background:
- Measles, a viral infection caused by morbillivirus, typically affects children but can present with ocular complications.
- Ophthalmologic manifestations, though uncommon, are primarily conjunctivitis and keratitis, with corneal involvement posing the most significant risk.
- Corneal involvement can range from superficial punctate keratitis to severe outcomes like perforation.
Observation:
- Three cases of acute keratitis in young adults during a measles epidemic were observed.
- Epithelial corneal involvement presented in various patterns: peripheral, central, or diffuse.
- All patients were treated with symptomatic topical therapy.
Findings:
- Measles-associated acute keratitis can affect young adults.
- The observed keratitis showed diverse patterns of epithelial involvement.
- Symptomatic topical treatment resulted in a favorable outcome for all reported cases.
Implications:
- Highlights the potential for measles to cause significant ocular morbidity in adults.
- Emphasizes the importance of recognizing and managing measles-related keratitis promptly.
- Suggests that symptomatic topical treatment can be effective in resolving measles-induced keratitis.
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