Related Experiment Video
Updated: Dec 25, 2025

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
Abdominal Distention and Emesis in a Term Neonate
Holly S Rose1, Alexandra K Monroe2, M Olivia Titus2
1Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina.
Necrotizing enterocolitis (NEC) is a severe condition that can affect full-term infants. Early recognition and emergency care are crucial, even without typical risk factors, as diagnosis can be challenging.
Area of Science:
- Neonatology
- Pediatric Surgery
- Emergency Medicine
Background:
- Necrotizing enterocolitis (NEC) is a critical gastrointestinal condition primarily affecting preterm infants, but also occurring in term neonates.
- A rare, rapidly fatal form, NEC totalis, affects nearly 10% of NEC cases.
- This case highlights NEC in a term infant without known risk factors.
Observation:
- A 24-day-old term infant presented with emesis, abdominal distension, tachycardia, and hypotension.
- Initial imaging was inconclusive, delaying diagnosis.
- The infant's condition rapidly deteriorated, necessitating exploratory laparotomy.
Findings:
- The infant was diagnosed with NEC totalis, a severe form of necrotizing enterocolitis.
- Despite aggressive management, the infant passed away within 6 days.
- This case underscores the diagnostic challenges of NEC in term infants.
Implications:
- Emergency physicians must consider NEC in term infants with severe gastrointestinal distress, even without typical risk factors.
- Prompt fluid resuscitation, antibiotics, and surgical consultation are vital.
- Timely diagnosis and intervention are critical for improving outcomes in neonatal gastrointestinal emergencies.
More Related Videos
05:33Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture
Published on: August 4, 2023
09:36Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
Published on: July 28, 2022
Related Concept Videos
Pathophysiology of Vomiting
Gastric Emptying
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...