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Murine Renal Transplantation Procedure
18:48

Murine Renal Transplantation Procedure

Published on: July 10, 2009

30.4K

UK national study of barriers to renal transplantation in children

Ji Soo Kim1,2, Matko Marlais3,2, Ramnath Balasubramanian4

  • 1Paediatric Nephrology, Great Ormond Street Hospital For Children NHS Foundation Trust, London, UK jisoo.kim@nhs.net.

Archives of Disease in Childhood
|April 4, 2020
PubMed

Insights

Barriers to pediatric kidney transplants include disease, donor availability, and child size. Addressing these, particularly donor access and psychosocial support, can improve pediatric renal transplantation outcomes.

Area of Science:

  • Pediatric Nephrology
  • Transplantation Medicine
  • Public Health

Background:

  • Access to pediatric renal transplantation is crucial for children with end-stage kidney disease (ESKD).
  • Identifying barriers is essential for improving transplant rates and patient outcomes.

Purpose of the Study:

  • To investigate access to pediatric renal transplantation.
  • To examine potential barriers within the pediatric renal transplantation process.

Main Methods:

  • A cross-sectional, multicentre, observational study was conducted.
  • Data were collected from 12 out of 13 UK pediatric nephrology centers.
  • Information on transplantation plans for children (<18 years) with ESKD was gathered.

Main Results:

  • 308 children with ESKD were included.
  • 45% were prepared for living donor transplantation; 27% were listed for deceased donor transplantation.
  • Key barriers included disease factors (36%), donor availability (27%), child size (20%), and psychosocial factors (19%).

Conclusions:

  • This study documented significant barriers to renal transplantation in children.
  • Modifiable factors, such as improving donor availability and addressing psychosocial support, can enhance pediatric transplantation rates.
Abstract

Keywords:
nephrologypaediatric practicetransplantation

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