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Updated: Dec 25, 2025

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
Published on: May 20, 2016
[CFD simulation study of aerodynamics in nasal cavity in a case of septal perforation]
D A Shcherbakov1, V V Kokareva1, N I Cheremnykh2
1Federal State Institution Russian Eye and Plastic Surgery Center, Ufa, Russia, 450075.
Abstract:
Perforation of the nasal septum remains an actual problem. The success of surgical closure of perforation of the nasal septum depends not only on the surgeon's skill, but also on the degree of disturbance of the nasal cavity physiology. Traditionally, CFD studies of nasal septal perforations are dedicated to the analysis of changes in speed value of the inhaled air depending on the size and localization of perforation of the nasal septum. But there is a lack of studies about warming and moistening of the inhaled air in a case of nasal septal perforation. These studies are necessary not only for studying the pathophysiology of perforation of the nasal septum, but also for planning surgery.
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