Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experimental observation of counter-intuitive features of photonic bunching.

Light, science & applications·2026
Same author

A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination.

Nucleic acids research·2026
Same author

High-efficiency grating couplers for vertical coupling in thin-film silicon nitride technology.

Scientific reports·2026
Same author

Experimental data reuploading with provable enhanced learning capabilities.

Science advances·2026
Same author

Decoding nucleic acid contributions to phase separation and ordering in biomolecular condensates.

Nucleic acids research·2026
Same author

Amplitude- and Phase-Programmable Dual-Color Photonic Chip for High-Contrast Structured Illumination Microscopy.

ACS photonics·2026

Related Experiment Video

Updated: Dec 25, 2025

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
11:38

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

8.3K

Integrated Optofluidic Chip for Oscillatory Microrheology.

Valerio Vitali1, Giovanni Nava2, Giuliano Zanchetta2

  • 1University of Pavia, Dept. of Electrical, Computer and Biomedical Engineering, Pavia, 27100, Italy.

Scientific Reports
|April 4, 2020
PubMed
Summary

This study introduces an on-chip optofluidic device for precise microrheology measurements of complex fluids. The flexible, low-cost system enables viscoelastic property analysis using minimal sample volumes.

More Related Videos

Fabrication and Testing of Microfluidic Optomechanical Oscillators
09:10

Fabrication and Testing of Microfluidic Optomechanical Oscillators

Published on: May 29, 2014

12.5K
Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.6K

Related Experiment Videos

Last Updated: Dec 25, 2025

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
11:38

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

8.3K
Fabrication and Testing of Microfluidic Optomechanical Oscillators
09:10

Fabrication and Testing of Microfluidic Optomechanical Oscillators

Published on: May 29, 2014

12.5K
Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.6K

Area of Science:

  • Optofluidics
  • Rheology
  • Biophysics

Background:

  • Microrheology is crucial for understanding complex fluid behavior.
  • Existing methods often require large sample volumes and are costly.
  • On-chip devices offer miniaturization and enhanced control.

Purpose of the Study:

  • To develop and demonstrate an on-chip optofluidic device for active oscillatory microrheology.
  • To enable measurements of viscoelastic properties with sub-microliter sample volumes.
  • To provide a low-cost, flexible platform for complex fluid analysis.

Main Methods:

  • Utilized optical forces from counterpropagating infrared laser beams on a microbead.
  • Integrated waveguides and an optical modulator fabricated via fs-laser writing on a glass substrate.
  • Employed an on-chip optofluidic microrheometer for active oscillatory measurements.

Main Results:

  • Successfully measured viscoelastic properties of complex fluids in the 0.01-10 Hz frequency range.
  • Demonstrated capability for measurements at varying temperatures.
  • Validated system performance using aqueous worm-like micelles (Cetylpyridinium Chloride/Sodium Salicylate).

Conclusions:

  • The developed on-chip optofluidic device offers a versatile and efficient tool for microrheological studies.
  • The system's low sample volume requirement and flexibility make it suitable for diverse complex fluid analyses.
  • This technology advances the field of microfluidic rheometry for scientific research.