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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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The experimental conditions in a gravimetric analysis should be optimized to maximize the particle size and purity of the obtained precipitate. Ideally, the concentration of the precipitating reagent should be low with effective stirring to maintain low relative supersaturation for the growth of large crystals. In homogeneous precipitation, the precipitant is slowly generated by a chemical reaction in the solution to avoid local reagent excesses. For example, urea decomposes gradually to...
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Cohort Profile: The Precipitating Events Project (PEP Study).

T M Gill1, L Han, E A Gahbauer

  • 1Thomas M. Gill, MD, Yale School of Medicine, Adler Geriatric Center, 874 Howard Avenue, New Haven, CT 06519, Telephone: (203) 688 9423 Fax: (203) 688 4209, Email: thomas.gill@yale.edu, Twitter: @MrDisability.

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Summary
This summary is machine-generated.

The Precipitating Events Project (PEP Study) tracks disability in older adults. It examines how illnesses and injuries impact the aging process, providing valuable data on elder health and longevity.

Keywords:
Longitudinal studydisabilityfrailtyfunctional assessmentolder persons

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Area of Science:

  • Gerontology
  • Epidemiology
  • Longitudinal Studies

Background:

  • The Precipitating Events Project (PEP Study) is a longitudinal study initiated in 1998.
  • It focuses on 754 community-living individuals aged 70 and older.
  • The study aims to understand the epidemiology of disability in older populations.

Purpose of the Study:

  • To rigorously evaluate the epidemiology of disability in older persons.
  • To elucidate the role of intervening illnesses and injuries on the disabling process.
  • To provide data for research on aging, frailty, and end-of-life care.

Main Methods:

  • Longitudinal study design with comprehensive home-based assessments every 18 months.
  • Monthly phone interviews with a 99% completion rate.
  • Annual data collection on healthcare utilization via Medicare claims linkage.

Main Results:

  • Data collected from March 1998 to June 2019.
  • High participant retention with 99% phone interview completion.
  • Extensive data available for 754 initially enrolled participants, with 702 deaths recorded.

Conclusions:

  • The PEP Study provides a rich dataset for investigating the aging process and disability.
  • Published research spans multiple high-priority areas including frailty, pain, and end-of-life.
  • The study welcomes proposals for data access from qualified investigators.