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Updated: Dec 25, 2025

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Published on: January 15, 2018

Correction: Directed evolution of gold nanoparticle delivery to cells.

Na Li¹, Timothy Larson, Hong H Nguyen

¹Department of Chemistry and Biochemistry, Institute for Cell and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA. andy.ellington@mail.utexas.edu.

Chemical Communications (Cambridge, England)

|April 4, 2020

Summary

This correction clarifies the directed evolution of gold nanoparticles for cellular delivery. It ensures accurate reporting of methods and results for nanoparticle research.

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Area of Science:

Nanotechnology
Biomedical Engineering
Materials Science

Background:

Gold nanoparticles (AuNPs) are increasingly utilized in biomedical applications, including targeted drug delivery and diagnostics.
Efficient delivery of AuNPs to specific cell types is crucial for their therapeutic and diagnostic efficacy.
Directed evolution offers a powerful strategy for optimizing nanoparticle properties for biological applications.

Purpose of the Study:

To correct and clarify the methodology and findings presented in the original publication regarding the directed evolution of gold nanoparticles.
To ensure the accurate representation of the engineered AuNPs' cellular delivery capabilities.
To provide a corrected reference for researchers in the field of nanoparticle-mediated cellular delivery.

Main Methods:

The correction pertains to the experimental procedures and data interpretation related to the directed evolution process.
Specific details regarding nanoparticle synthesis, characterization, and cell targeting assays are addressed.
The revised information ensures the reproducibility and validity of the study's findings.

Main Results:

The correction clarifies the observed cellular uptake efficiencies and targeting specificities of the evolved gold nanoparticles.
Accurate data presentation is essential for understanding the performance of these nanomaterials in biological systems.
The revised findings support the potential of directed evolution in creating advanced nanoparticle delivery systems.

Conclusions:

The corrected information reinforces the significance of directed evolution in tailoring nanomaterials for enhanced cellular delivery.
Accurate scientific reporting is paramount for advancing the field of nanomedicine.
This correction ensures the integrity of the scientific record concerning gold nanoparticle development.