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Sexual dysfunction in Huntington's Disease - a systematic review

Klaudia Szymuś1, Artur Bystrzyński2, Magdalena Kwaśniak-Butowska3,4,5

  • 1Medical University of Gdansk, Student of Faculty of Medicine, Marii Skłodowskiej-Curie 3a, 80-210 Gdańsk, Poland. szymus.klaudia@gmail.com.

Neurologia I Neurochirurgia Polska
|April 4, 2020
PubMed

Insights

Sexual dysfunction is common in Huntington

Area of Science:

  • Neurology
  • Sexual Medicine

Background:

  • Huntington's Disease (HD) is a progressive neurodegenerative disorder.
  • HD manifests with motor, cognitive, and behavioral symptoms, often including sexual dysfunction.

Purpose of the Study:

  • To comprehensively review current knowledge on sexual dysfunction in Huntington's Disease.
  • To highlight the prevalence and types of sexual disorders experienced by HD patients.

Main Methods:

  • Systematic literature search of PubMed and Scopus databases.
  • Inclusion of original studies published after 1994 (post-genetic test diagnosis).

Main Results:

  • Nine studies met the inclusion criteria.
  • High prevalence of sexual disorders in HD patients: hypoactive sexual disorder (53-83%), erectile dysfunction (48-74%), lubrication issues (53-83%), and orgasmic dysfunction (35-78%).

Conclusions:

  • Sexual dysfunction in HD is prevalent and likely underestimated.
  • Addressing sexual health is crucial for improving the quality of life for HD patients and their caregivers.
  • Potential biases include social taboos, medication effects, and methodological limitations in existing studies.
Abstract

Keywords:
Huntington’s Diseasedepressionsexual disordersexual dysfunctionsexuality

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