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The effects of the wenyang huoxue method on coronary heart disease heart failure: A protocol for systematic review

Wenbo Han1, Yong Zhao1, Yahong Wang1

  • 1Dongzhimen Hospital, Affiliated Hospital of Beijing University of Chinese Medcine.

Medicine
|April 4, 2020
PubMed

Insights

This review evaluates the Wenyang Huoxue method for coronary heart disease (CHD) with heart failure (HF). It aims to determine if this treatment effectively improves cardiac function and safety in patients.

Area of Science:

  • Cardiology
  • Traditional Chinese Medicine

Background:

  • Coronary heart disease (CHD) is a leading cause of heart failure (HF).
  • The Wenyang Huoxue method shows potential for improving cardiac function in CHD patients with HF.
  • Systematic evaluation of its efficacy and safety is lacking.

Purpose of the Study:

  • To systematically evaluate the efficacy and safety of the Wenyang Huoxue method for treating CHD complicated with HF.
  • To provide evidence-based support for the clinical application of this traditional Chinese medicine method.

Main Methods:

  • Comprehensive literature search across multiple databases (CNKI, Wanfang, CBM, CSTJ, PubMed, EMBASE, Cochrane Library) from January 2000 to September 2019.
  • Inclusion of randomized controlled trials, clinical trial registrations, grey literature, conference abstracts, and reference lists.
  • Meta-analysis using RevMan 5.3.5, employing fixed or random effects models based on heterogeneity testing. Primary outcome: total effective rate in cardiac function. Secondary outcomes: 6-minute walk test, left ventricular ejection fraction, and plasma brain natriuretic peptide.

Main Results:

  • This systematic review and meta-analysis will provide a high-quality, comprehensive evaluation of the Wenyang Huoxue method's efficacy and safety.
  • The findings will synthesize current evidence on the treatment's impact on cardiac function and related clinical indicators.

Conclusions:

  • This systematic review will determine the evidence supporting the Wenyang Huoxue method as an effective intervention for patients with CHD complicated by HF.
  • The study aims to clarify the role of this traditional Chinese medicine approach in managing CHD-induced heart failure.
Abstract

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