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Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...

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Updated: Jun 26, 2026

Collecting Variable-concentration Isothermal Titration Calorimetry Datasets in Order to Determine Binding Mechanisms
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The Automation Technique Lab-In-Syringe: A Practical Guide.

Burkhard Horstkotte1, Petr Solich1

  • 1Department of Analytical Chemistry, Charles University, Faculty of Pharmacy, Akademika Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.

Molecules (Basel, Switzerland)
|April 5, 2020
PubMed
Summary

Lab-In-Syringe automation offers versatile sample preparation, especially for liquid-phase microextraction. This review guides researchers on system setup, configurations, and method development for this popular flow technique.

Failed At:

2026-06-19T13:38:31.259553+00:00

Keywords:
3D printing of instrument elementsLab-In-Syringeautomation of sample pretreatmentpotentials and troublessystem setup and operation modestips and tricks in method development

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