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SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far
Firas A Rabi1, Mazhar S Al Zoubi2, Ghena A Kasasbeh3
1Department of Clinical Sciences, Faculty of Medicine, Yarmouk University, Irbid 21163, Jordan.
Pathogens (Basel, Switzerland)
|April 5, 2020
Summary
A novel coronavirus, SARS-CoV-2, emerged in Wuhan, China, causing COVID-19. This summary reviews current knowledge on the virus, its pathogenesis, and the global response.
Area of Science:
- * Virology and Epidemiology
- * Infectious Diseases
Background:
- * Emergence of a novel coronavirus (SARS-CoV-2) in Wuhan, China, in December 2019.
- * Association with a live animal market and rapid global spread.
- * Recurrence of coronavirus epidemics, reminiscent of SARS and MERS.
Purpose of the Study:
- * To summarize current scientific knowledge regarding SARS-CoV-2 and COVID-19.
- * To provide an overview of the virus's origin, pathogenesis, and risk factors.
- * To highlight ongoing research in treatment and vaccine development.
Main Methods:
- * Review of clinical, serological, and molecular data.
- * Synthesis of information on the novel coronavirus and the disease it causes.
- * Analysis of the global public health response and scientific community's efforts.
Main Results:
- * Identification of SARS-CoV-2 as the causative agent of COVID-19.
- * Confirmation of rapid human-to-human transmission and global dissemination.
- * Recognition of the close relationship between SARS-CoV-2 and SARS-CoV.
Conclusions:
- * COVID-19 represents a significant global health challenge.
- * Ongoing research is crucial for understanding and combating the pandemic.
- * International collaboration is essential for developing effective treatments and vaccines.
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