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Updated: Dec 25, 2025

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
EVALI and the Pulmonary Toxicity of Electronic Cigarettes: A Review
Lydia Winnicka1, Mangalore Amith Shenoy2
1Department of Pulmonary and Critical Care Medicine, NYU Winthrop Hospital, 222 Station Plaza North, Suite 400, Mineola, NY, 11501, USA. lydiawinnicka@gmail.com.
Abstract:
Electronic cigarettes are a novel and emerging product increasingly used by the general public. However, despite their popularity, they remain poorly studied and with likely serious health risks. EVALI, or "electronic cigarette or vaping product use-associated lung injury," is a recently described entity at the forefront of current investigations. Though EVALI has been linked to vitamin E acetate, a constituent of THC vaping products, electronic cigarettes likely pose a host of other pulmonary toxicities. The presentation, diagnostic work-up, treatment, and pathophysiology of EVALI are herein described, as well as the general pulmonary toxicity profile of electronic cigarettes.
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