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Pattern of allergic sensitization in chronic rhinitis: A 19-year retrospective study
Pongsakorn Tantilipikorn1, Bannapuch Pinkaew1, Kanokporn Talek1
1Division of Rhinology & Allergy, Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Asian Pacific Journal of Allergy and Immunology
|April 6, 2020
Summary
Allergic sensitization patterns in Thai adults show house dust mites and sedge as common allergens. Despite a rise in sensitization prevalence, the overall pattern remained stable over 19 years, with symptoms significantly impacting quality of life.
Area of Science:
- Allergy and Immunology
- Clinical Medicine
- Epidemiology
Background:
- Understanding allergic sensitization patterns is crucial for effective patient care.
- This study examines long-term trends in allergen sensitization.
Purpose of the Study:
- To analyze the long-term pattern of allergen skin prick test (SPT) sensitization in adult rhinitis patients in Thailand.
- To identify common indoor and outdoor allergens and assess their impact on quality of life (QoL).
Main Methods:
- Retrospective review of medical records of 6,517 adult rhinitis patients from 1998-2017.
- Analysis of skin prick test (SPT) results, clinical symptoms, and QoL.
- Descriptive statistics and multivariate linear regression were employed.
Main Results:
- 59.4% of patients had positive SPT, with 83.7% exhibiting polysensitization.
- Dermatophagoides pteronyssinus (house dust mite) and sedge were the most frequent indoor and outdoor allergens, respectively.
- Sensitization prevalence increased from 66.8% to 73.7% (2013-2017), though the overall pattern was stable; allergic symptoms significantly affected QoL.
Conclusions:
- House dust mites and sedge are the predominant indoor and outdoor allergens in this population.
- No significant long-term change in sensitization patterns was observed, but prevalence increased recently.
- Allergic symptoms substantially impact the quality of life for chronic rhinitis patients.
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