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Related Experiment Videos

Neonatal listeriosis.

C E Ahlfors, B W Goetzman, C C Halsted

    American Journal of Diseases of Children (1960)
    |April 1, 1977
    PubMed
    Summary

    Neonatal listeriosis can be severe, with one infant death. Prompt antibiotic and ventilatory support improved survival rates for affected newborns.

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    Area of Science:

    • Neonatal Medicine
    • Infectious Diseases
    • Pediatrics

    Background:

    • Neonatal listeriosis is a serious infection.
    • Maternal complications like fever and meconium-stained amniotic fluid are common.
    • The granulomatous form of listeriosis can be fatal.

    Purpose of the Study:

    • To report on the diagnosis and treatment of neonatal listeriosis.
    • To identify factors contributing to survival in affected infants.

    Main Methods:

    • Retrospective case series of five neonatal listeriosis cases.
    • Analysis of maternal and infant clinical data.
    • Evaluation of treatment strategies including antibiotics and mechanical ventilation.

    Main Results:

    • Five cases of neonatal listeriosis over 13 months.
    • One infant mortality due to the granulomatous form.
    • Four infants required mechanical ventilation.
    • Two survivors with severe pneumonia responded to tolazoline hydrochloride for hypoxemia.

    Conclusions:

    • Early antibiotic administration is crucial.
    • Aggressive ventilatory and pharmacological support are vital for survival.
    • Tolazoline hydrochloride may be beneficial for persistent hypoxemia in neonatal listeriosis survivors.

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