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Updated: Dec 25, 2025

Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms
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γ-Secretase inhibitors and modulators: Mechanistic insights into the function and regulation of γ-Secretase

Pengju Nie1, Abhishek Vartak2, Yue-Ming Li1

  • 1Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Pharmacology program, Weill Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.

Seminars in Cell & Developmental Biology
|April 7, 2020
PubMed

Keywords:
InhibitorMechanismModulatorPhoto affinity labelingγ-Secretase

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