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Multiple Cerebral Hemorrhages With Microbleeds in Intravascular Large B-Cell Lymphoma
Masamune Kimura1, Satoru Fujiwara1, Atsushi Tanaka2
1Kobe City Medical Center General Hospital, Department of Neurology, Kobe, Hyogo, Japan.
Abstract:
This is an extremely rare reported case of intravascular large B-cell lymphoma (IVLBCL) presenting with acute hemorrhages and numerous microbleeds. An 80-year-old man presented with consciousness disturbances after convulsion. Computed tomography revealed multiple hemorrhages, and susceptibility-weighted imaging (SWI) demonstrated numerous microbleeds. Brain biopsy showed CD20-positive cells in small vessels; accordingly, IVLBCL was diagnosed. IVLBCL should be considered as a differential diagnosis in multiple cerebral hemorrhages and microbleeds.
