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Updated: Dec 24, 2025

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
Published on: September 30, 2022
Triple-sensitivity high-spatial-resolution X-ray computed tomography using a cadmium-telluride detector and its
Sohei Yoshida1, Eiichi Sato2, Yasuyuki Oda2
1Department of Radiology, School of Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, 028-3694, Japan.
Abstract:
To observe blood vessels at high contrasts, we constructed a first-generation triple-sensitivity X-ray computed tomography (TS-CT) scanner using a cadmium-telluride (CdTe) detector and a triple-amplifying system. X-ray photons are absorbed by the CdTe crystal, and the electric charges produced by photons are converted into voltages using a current-to-voltage (I-V) amplifier, and the I-V output is amplified by a voltage-to-voltage (V-V) amplifier. The V-V output 1 is sent to a dual V-V amplifier through a 5.0-m-length coaxial cable and amplified to two-different outputs of 2 and 3. The three outputs 1-3 are sent to a personal computer through an analog-to-digital converter to reconstruct three tomograms simultaneously. In the TS-CT, the scattering photons from the object are extremely reduced using a 0.5-mm-diameter lead pinhole behind the object. The translation and rotation steps were 0.1 mm and 0.5°, respectively, and the spatial resolutions were 0.25 × 0.25 mm2. The scanning time was 19.6 min, and blood vessels were visible using gadolinium contrast media. In particular, the effective photon energy increased with increasing amplification factor of the amplifier caused by beam hardening of the object.
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