Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Weak associations in environmental epidemiology.

B Brunekreef1, L Dijkstra, P Fischer

  • 1Department of Environmental Health, University of Wageningen, The Netherlands.

International Journal of Epidemiology
|December 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mental healthcare expenditure in the Netherlands by urbanicity and neighbourhood socioeconomic status and interactions with age over the period 2015-2020.

Archives of public health = Archives belges de sante publique·2026
Same author

Birth Cohort Studies of Long-Term Exposure to Ambient Air Pollution in Early Life and Development of Asthma in Children and Adolescents from Denmark.

Research report (Health Effects Institute)·2024
Same author

Young adults, particularly young women, account for an increasingly large share of Dutch mental healthcare expenditure over the period between 2015 and 2021.

Epidemiology and psychiatric sciences·2024
Same author

Long-Term Exposure to AIR Pollution and COVID-19 Mortality and Morbidity in DENmark: Who Is Most Susceptible? (AIRCODEN).

Research report (Health Effects Institute)·2024
Same author

The burden of heat-related mortality attributable to recent human-induced climate change.

Nature climate change·2021
Same author

Short-term effects of air pollution and temperature on cattle mortality in the Netherlands.

Preventive veterinary medicine·2019

This study explores methods to improve environmental epidemiology research by reducing errors and focusing on low-risk populations. It discusses the practical challenges and benefits of these enhanced study designs.

Area of Science:

  • Environmental epidemiology
  • Biostatistics
  • Public health research methodology

Background:

  • Weak associations in epidemiological studies can be challenging to interpret.
  • Enhancing study designs is crucial for strengthening evidence.
  • Existing methods include reducing non-differential misclassification and restricting study populations.

Purpose of the Study:

  • To discuss the prospects and problems of enhanced study designs in environmental epidemiology.
  • To evaluate the application of specific design enhancements using examples from the authors' research.
  • To provide insights into improving the validity of environmental health studies.

Main Methods:

  • Review of methodological suggestions for strengthening epidemiological associations.

Related Experiment Videos

  • Application of these suggestions in the context of environmental epidemiology.
  • Case examples from the authors' research to illustrate practical implementation.
  • Discussion of challenges such as selection bias and confounding in restricted populations.

    • Main Results:

    • Implementing design enhancements can improve the ability to detect weak associations.
    • Restriction to low-risk populations may introduce selection bias and limit generalizability.
    • Reduction of non-differential misclassification is a valuable but sometimes difficult strategy.
    • The effectiveness of these methods depends on careful consideration of potential biases.

    Conclusions:

    • Enhanced study designs offer potential benefits for environmental epidemiology but require careful planning.
    • Addressing challenges like selection bias is critical for valid results.
    • The discussed methods provide a framework for improving the quality of environmental health research.