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Updated: Dec 24, 2025

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Complementary and Alternative Medicine for Postoperative Pain: A Systematic Review
Caitlin J Bakker1, Kelsey L Wise1, Benjamin R Williams1
1Health Sciences Libraries (C.J.B.) and Department of Orthopaedic Surgery (K.L.W., B.R.W., and M.F.S.), University of Minnesota, Minneapolis, Minnesota.
Evidence is insufficient to confirm if complementary and alternative medicines effectively manage postoperative pain or reduce opioid use in orthopaedic surgery. More research is needed to establish their efficacy.
Area of Science:
- Orthopaedic Surgery
- Pain Management
- Evidence-Based Medicine
Background:
- Postoperative pain management is a significant challenge in orthopaedic surgery.
- Inadequate pain control can lead to adverse patient outcomes and prolonged opioid use.
- Complementary and alternative medicine (CAM) is popular for chronic pain, but its postoperative efficacy is unproven.
Purpose of the Study:
- To systematically review the literature on the efficacy of CAM for postoperative pain management in orthopaedic surgery.
- To evaluate the impact of CAM on postoperative opioid consumption.
Main Methods:
- Systematic literature review of 10 databases.
- Extraction of data on pain measurement and opioid prescriptions.
- Analysis of 8 relevant studies (5 randomized, 3 non-randomized).
Main Results:
- Five studies indicated significant reductions in postoperative pain (p < 0.05).
- Two studies showed significant differences in postoperative opioid consumption (p < 0.05).
- Heterogeneity and potential bias were noted across studies, precluding meta-analysis.
Conclusions:
- Insufficient evidence exists to support the use of CAM for postoperative pain management in orthopaedic surgery.
- The efficacy of CAM as an alternative to opioid use requires further investigation.
- High-quality research is needed to address the current evidence gap.
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