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Related Experiment Video

Updated: Dec 24, 2025

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Clinical care is evolving: The microbiome for advanced practice nurses.

Mark B Lockwood1, Stefan J Green2

  • 1Department of Biobehavioral Health Science, University of Illinois at Chicago, College of Nursing, Chicago, Illinois.

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Summary

Human health is intimately linked with trillions of microbes, forming the microbiome. Understanding this complex relationship is crucial for healthcare professionals, especially advanced practice nurses, to improve patient outcomes.

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Area of Science:

  • Microbiology
  • Human Health
  • Microbiome Research

Background:

  • Humans host over 37 trillion microbes, forming a complex microbiome.
  • Microbial cells in the body are roughly equivalent to mammalian cells.
  • The microbiome's genetic content vastly exceeds the human genome, influencing health and survival.

Purpose of the Study:

  • To highlight the significance of the human microbiome in health and disease.
  • To underscore the factors influencing microbiome composition.
  • To emphasize the role of advanced practice nurses in microbiome-related healthcare.

Main Methods:

  • Review of existing scientific literature on the human microbiome.
  • Analysis of the microbiome's genetic contribution to human health.
  • Exploration of factors impacting microbiome diversity and richness.

Main Results:

  • The microbiome plays a critical role in producing essential molecules for human survival.
  • Factors like birth mode, diet, and medications significantly alter microbiome composition.
  • Microbiome research is rapidly evolving, with profound implications for clinical practice.

Conclusions:

  • The human microbiome is integral to health, ranging from symbiotic to pathogenic interactions.
  • Advanced practice nurses must educate themselves on the microbiome to effectively advocate for patients.
  • Integrating microbiome knowledge into clinical practice is essential for future healthcare.
  • Nurses are vital in educating patients about the microbiome, environment, and health connection.