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The epidemiologic characteristics and associated risk factors of preterm birth from 2004 to 2013 in Taiwan
Yu-Kang Chang1, Yuan-Tsung Tseng2, Kow-Tong Chen3,4
1Department of Radiology, Chi Mei Medical Center, Liouying, Tainan, Taiwan.
Insights
The preterm birth rate in Taiwan increased significantly from 2004 to 2013. Key risk factors include advanced maternal age, multiple pregnancies, and prior preterm birth history, necessitating targeted interventions.
Area of Science:
- Obstetrics and Gynecology
- Public Health
- Epidemiology
Background:
- Global increase in preterm birth rates observed.
- Preterm infants face heightened risks for CNS, respiratory, and gastrointestinal complications.
- Understanding regional trends and risk factors is crucial for intervention strategies.
Purpose of the Study:
- To investigate the epidemiologic characteristics of preterm birth in Taiwan.
- To identify associated risk factors contributing to preterm birth in the Taiwanese population.
Main Methods:
- Utilized the National Health Insurance Research (NHIR) database for obstetric data.
- Included all live births in Taiwan between 2004 and 2013.
- Employed multiple logistic regression analyses to determine risk factors.
Main Results:
- Total of 130,362 live births analyzed from 2004-2013.
- Annual preterm birth rate rose from 3.33% to 5.11% (5.3% increase).
- Identified nulliparity, multifetal pregnancy, advanced maternal age, previous preterm birth, drug abuse, and medical complications as significant risk factors (p<0.05).
Conclusions:
- Taiwan experienced a notable increase in preterm birth proportion from 2004 to 2013.
- Preterm birth is associated with increased infant morbidity and mortality.
- A comprehensive program is needed to identify high-risk pregnancies for effective prevention.
Background:
The rate of preterm birth has been increasing worldwide. Most preterm babies are at an increased risk of central nervous system impairments as well as respiratory and gastrointestinal complications. The aim of this study was to investigate the epidemiologic characteristics of and associated factors contributing to preterm birth in Taiwan.
Methods:
Information on obstetric antecedents and risk factors for preterm birth in pregnant women was obtained from the National Health Insurance Research (NHIR) database provided by the Taiwan National Health Research Institute. All live births from 2004 to 2013 in Taiwan were included in this study.
Results:
A total of 130,362 live births from 2004 to 2013 were included in this study. Overall, the average annual rate of preterm births increased by 5.3% (from 3.33% in 2004 to 5.11% in 2013). Multiple logistic regression analyses showed that nulliparous women, multifetal pregnancies, advanced mother age, history of preterm birth, history of maternal drug abuse/dependence, and maternal medical complications were positively associated with an increased risk of preterm birth (all p-values< 0.05).
Conclusion:
The overall proportion of preterm births increased from 2004 to 2013 in Taiwan. Babies born preterm had a higher risk of developing morbidities and mortalities. The development of a comprehensive program to identify the high-risk group is needed for effective interventions to prevent premature birth.
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