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Updated: Dec 24, 2025
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China
Xiaoming Li1, Wenbing Zeng2, Xiang Li2
1Department of Radiology, First Affiliated Hospital to Army Medical University, Chongqing, China.
Insights
Chest CT imaging is crucial for diagnosing COVID-19, revealing characteristic multifocal peripheral ground glass or mixed consolidation patterns. These findings in coronavirus disease 2019 (COVID-19) patients can rapidly evolve over a short period.
Area of Science:
- Radiology
- Infectious Diseases
- Pulmonology
Background:
- The emergence of coronavirus disease 2019 (COVID-19) in Wuhan necessitated understanding its impact in other regions.
- Southwest China reported confirmed cases of COVID-19, prompting investigation into local patient characteristics.
Purpose of the Study:
- To delineate the specific imaging manifestations of hospitalized COVID-19 patients in Southwest China.
- To correlate clinical and radiological findings in confirmed COVID-19 cases.
Main Methods:
- Retrospective analysis of chest CT images from 131 hospitalized COVID-19 patients across 3 Chinese hospitals.
- Evaluation of common clinical symptoms and CT imaging features, including lesion characteristics and evolution.
Main Results:
- Most patients (76%) had close contact with Wuhan residents. Common symptoms included cough and fever.
- Chest CT revealed bilateral, peripheral, multifocal lesions, often involving multiple lobes. Ground glass opacities and consolidation were frequent.
- CT findings evolved rapidly; 73% of cases showed changes within 3.5 days, with progression observed in 46%.
Conclusions:
- Chest CT is vital for diagnosing COVID-19.
- The characteristic imaging pattern of multifocal peripheral ground glass or mixed consolidation is highly suggestive of COVID-19.
- Rapid temporal changes in CT findings are a key feature of COVID-19 pneumonia.
Background:
Since the first case of a coronavirus disease 2019 (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Southwest China. The aim of this study was to describe the imaging manifestations of hospitalized patients with confirmed COVID-19 infection in southwest China.
Methods:
In this retrospective study, data were collected from 131 patients with confirmed coronavirus disease 2019 (COVID-19) from 3 Chinese hospitals. Their common clinical manifestations, as well as characteristics and evolvement features of chest CT images, were analyzed.
Results:
A total of 100 (76%) patients had a history of close contact with people living in Wuhan, Hubei. The clinical manifestations of COVID-19 included cough, fever. Most of the lesions identified in chest CT images were multiple lesions of bilateral lungs, lesions were more localized in the peripheral lung, 109 (83%) patients had more than two lobes involved, 20 (15%) patients presented with patchy ground glass opacities, patchy ground glass opacities and consolidation of lesions co-existing in 61 (47%) cases. Complications such as pleural thickening, hydrothorax, pericardial effusion, and enlarged mediastinal lymph nodes were detected but only in rare cases. For the follow-up chest CT examinations (91 cases), We found 66 (73%) cases changed very quickly, with an average of 3.5 days, 25 cases (27%) presented absorbed lesions, progression was observed in 41 cases (46%), 25 (27%) cases showed no significant changes.
Conclusion:
Chest CT plays an important role in diagnosing COVID-19. The imaging pattern of multifocal peripheral ground glass or mixed consolidation is highly suspicious of COVID-19, that can quickly change over a short period of time.
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