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Effectiveness of transcutaneous tibial nerve stimulation at two different thresholds for overactive bladder symptoms
Aline Teixeira Alve1, Patrícia Azevedo Garcia2, Raquel Henriques Jácomo3
1University of Brasilia, Centro Metropolitano, Conjunto A, Lote 01, Universidade De Brasília - Campus Ceilândia, Zip-code: 72220-90 Brasília, DF, Brazil.
Objectives:
To compare the effectiveness of transcutaneous tibial nerve stimulation (TTNS) at two different current amplitude thresholds (sensory and motor) in terms of urinary habit, symptoms and the degree of discomfort of overactive bladder (OAB) in older women.
Study Design:
This is a randomized, controlled, 3-arm blinded trial. One hundred and one patients attending secondary care with OAB were randomized into one of three groups: group 1, TTNS sensitivity threshold (n = 39); group 2, TTNS motor threshold (n = 33); and control group 3 (n = 29).
Main Outcome Measures:
Participants allocated to groups 1 and 2 had 8 sessions of TTNS for 30 min, twice a week. Group 3 received no intervention. The results measured were the symptoms of overactive bladder (ICIQ-OAB, overall score), bother scales (to indicate the impact of individual symptoms for the patient) and urinary habit (3-day bladder diary). A blind assessor measured outcomes at baseline and 5 weeks after randomization.
Results:
After five weeks, a statistically significant difference between group 3 (control) and group 1 (TTNS sensitivity threshold) and group 2 (TTNS motor threshold) was observed in the intergroup analysis, but no difference in the outcomes analyzed was detected between the two groups receiving intervention (groups 1 and 2).
Conclusion:
TTNS is effective in the treatment of OAB in older women, with no difference between the sensitivity and motor thresholds.
Clinical Trial Registration Number:
Registro Brasileiros de Ensaios Clínicos (RBR-39DZ5V).
