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Measuring Rates of Herbicide Metabolism in Dicot Weeds with an Excised Leaf Assay
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Multicomponent reactions in crop protection chemistry.
1Syngenta Crop Protection AG, Chemical Research, Schaffhauserstrasse 101, CH-4332 Stein, Switzerland.
Bioorganic & Medicinal Chemistry
|April 8, 2020
Summary
Multicomponent reactions are crucial for synthesizing agrochemicals like herbicides, fungicides, and insecticides. This review details key reactions and their applications in creating active compounds.
Area of Science:
- Organic Chemistry
- Agrochemical Science
Background:
- Multicomponent reactions (MCRs) offer efficient synthetic routes.
- Agrochemicals are vital for crop protection.
Purpose of the Study:
- To review the significance of MCRs in agrochemical synthesis.
- To highlight key MCRs and their applications in creating herbicidal, fungicidal, and insecticidal compounds.
Main Methods:
- Literature review of multicomponent reactions.
- Analysis of reaction mechanisms and applications in agrochemical synthesis.
Main Results:
- Detailed overview of Biginelli, Bucherer-Bergs, Hantzsch, Kabachnik-Fields, Mannich, Passerini, Petasis, Strecker, Ugi, and Willgerodt-Kindler reactions.
- Presentation of MCR applications in synthesizing active agrochemical compounds.
- Report on the mode of action and biological activity of synthesized compounds.
Conclusions:
- MCRs are highly significant for the efficient synthesis of diverse agrochemicals.
- The reviewed reactions provide versatile pathways to herbicidally, fungicidally, and insecticidally active compounds.
Keywords:
AgrochemicalCrop protectionFungicideHerbicideInsecticideMannich reactionMulticomponent reactionUgi reactionMore Related Videos
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