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Risk factors and outcomes of sepsis-associated delirium in intensive care unit patients: A secondary data analysis
Yeunwoo Kim1, Yinji Jin1, Taixian Jin1
1College of Nursing, The Catholic University of Korea, Seoul, Republic of Korea.
Objective:
To identify the risk factors of sepsis-associated delirium and determine their effect on intensive care unit adult patient outcomes.
Design:
A secondary analysis of data from system development studies.
Setting:
Korean intensive care unit patients in a university hospital who were diagnosed with sepsis.
Methods:
The risk factors for sepsis-associated delirium were classified into patient factors and sepsis clinical features and were analysed using hierarchical logistic regression analysis. Outcomes included in-hospital mortality, 30-day in-hospital mortality, duration of mechanical ventilation, length of stay in the intensive care unit, length of hospital stay, total medical expenses, discharge placement, re-hospitalisation and visits to the emergency department after discharge.
Results:
The risk factor for sepsis-associated delirium including patients aged 65 ≥years, dependent activity and high nursing needs (patient factors), low level of consciousness, tachypnoea, and thrombocytopaenia (clinical features of sepsis). Use of vasopressors/inotropes and albumin decreased the risk of sepsis-associated delirium. Mechanical ventilation duration was prolonged and discharge to skilled nursing facilities was increased by sepsis-associated delirium.
Conclusions:
The risk factors for sepsis-associated delirium increased as the severity of condition for patients with sepsis increased. Early identification of risk factors associated with sepsis-associated delirium may improve patient outcomes.
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