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Author Spotlight: Advancing Mitochondrial Research - mtHyper7 Biosensor for Subcellular Analysis
Published on: June 2, 2023
A near-infrared emission fluorescent probe with multi-rotatable moieties for highly sensitive detection of
Yanyan Ma1, Yuping Zhao, Rui Guo
1Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, P. R. China. weiyinglin2013@163.com.
Abstract:
A near-infrared emission fluorescent viscosity probe (TPE-V) which contains multi-rotatable moieties has been developed for the first time. TPE-V exhibited a large Stokes shift (190 nm) and a large enhancement in fluorescence intensity (100-fold) in response to viscosity. Moreover, TPE-V was successfully applied for the detection of mitochondrial viscosity in an inflammatory cell model.

