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Updated: Dec 24, 2025
Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications
Published on: June 2, 2017
Fabrication of micron-sized BSA-imprinted polymers with outstanding adsorption capacity based on poly(glycidyl
Yufei Wang1, Jingjing Zhou, Chen Wu
1MOE Key Laboratory of Material Physics and Chemistry under Extraordinary Conditions, School of Natural and Applied Science, Northwestern Polytechnical University, Xi'an 710072, P. R. China. qyzhang@nwpu.edu.cn.
Abstract:
Monodisperse poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres have been fabricated by seed polymerization. From the SEM images, it is known that the obtained PGMA/PS microspheres have three different morphologies: raspberry-shaped, golf-shaped and porous structures. Based on the successful fabrication of these micropheres, bovine serum albumin (BSA)-imprinted PGMA/PS microspheres were fabricated via dopamine auto-polymerization in alkaline solution. Because dopamine does not affect the validity of the protein structure, the imprinted cavity structure on the surface of the MIPs can match the template protein molecules completely. The obtained micron-sized BSA-imprinted PGMA/PS microspheres have an excellent saturation adsorption capacity (Q = 72.7 mg g-1) and good selective adsorption for BSA (IF = 4.6).
