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Updated: Dec 24, 2025

Transplantation Into the Mouse Ovarian Fat Pad
Published on: September 7, 2016
Multiple malignant transformations of an ovarian mature cystic teratoma
Kristen Cagino1, Daniel Levitan2, Nina Schatz-Siemers2
1Department of Gynecologic Oncology, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10021, USA.
Background:
Malignant transformation of mature cystic teratomas (MCTs) is a rare phenomenon. The most common histology of a malignant transformation is squamous cell carcinoma, and there are limited reports of multiple malignancies arising in a single MCT. Further data are necessary to guide management of these atypical cases.
Case:
We present the case of a 48-year-old with MCT containing a malignant papillary thyroid carcinoma (PTC) arising in the context of struma ovarii and a carcinoid tumour.
Conclusion:
Malignant transformations of MCTs are exceedingly rare with no guidelines on management. We use this case to demonstrate an approach for the workup and management of malignantly transformed MCTs.
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