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Severe Rhabdomyolysis in a Pediatric Patient after Coxsackie B Virus Infection without Acute Renal Failure: A Case
Ahmad Soliman1, Supriya Bisht1, Kokila Jeyamurugan1
1Pediatrics, Brookdale University Medical Center, New York City, USA.
Insights
Severe rhabdomyolysis, a muscle breakdown condition, occurred in a 14-year-old girl following a Coxsackie B viral infection. Fortunately, she did not develop acute renal failure, a common complication.
Area of Science:
- Medical Case Study
- Virology
- Nephrology
Background:
- Rhabdomyolysis involves skeletal muscle breakdown, releasing enzymes into circulation.
- This can lead to severe complications like acute renal failure (ARF).
- Viral infections are common causes in children, while trauma and exercise affect adolescents.
Observation:
- A 14-year-old female presented with severe rhabdomyolysis.
- The condition followed a recent Coxsackie B viral infection.
- The patient did not exhibit signs of acute renal failure.
Findings:
- Coxsackie B virus can trigger severe rhabdomyolysis in adolescents.
- The absence of acute renal failure in this case is noteworthy.
- This highlights the variable clinical presentation of viral-induced rhabdomyolysis.
Implications:
- Understanding viral triggers for rhabdomyolysis is crucial for early diagnosis.
- Prompt recognition may prevent severe complications like acute renal failure.
- Further research into Coxsackie B's role in rhabdomyolysis is warranted.
Abstract:
Rhabdomyolysis is a condition resulting from the breakdown of skeletal muscle fibers with leakage of muscle enzymes into the circulation. The degraded muscle components in the circulation can lead to lethal complications as acute renal failure (ARF). In younger children, viral infections tend to be the major cause while trauma and exercise are the important ones in adolescents. Several viruses such as influenza A & B, parainfluenza and coxsackie have been implicated in causing rhabdomyolysis. We report a case of a 14-year-old girl with severe rhabdomyolysis after recent Coxsackie B infection without acute renal failure.
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