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Bladder Metastasis from Breast Cancer: A Systematic Review
Uday Karjol1, Pavan Jonnada1, Sushma Cherukuru2
1Surgical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, IND.
Cureus
|April 8, 2020
Summary
Breast cancer metastasis to the urinary bladder is rare, often linked to invasive lobular carcinoma. Early diagnosis is key for managing symptoms like hematuria and voiding dysfunction.
Area of Science:
- Oncology
- Urology
Background:
- Breast cancer is a leading cause of cancer death in women, primarily due to metastasis.
- Metastasis to the urinary bladder from breast cancer is infrequently documented.
Purpose of the Study:
- To systematically review and analyze reported cases of breast cancer metastasis to the urinary bladder.
- To identify diagnostic and treatment planning clues for physicians.
Main Methods:
- Systematic literature review.
- Analysis of clinical and pathological data from reported cases.
Main Results:
- Urinary bladder metastases are more common in invasive lobular carcinoma.
- Presentations range from asymptomatic to symptomatic, with hematuria and voiding dysfunction being common.
- Data analyzed included epidemiology, spread patterns, symptoms, pathology, hormonal status, diagnostics, management, and outcomes.
Conclusions:
- This review provides insights into the incidence, clinical presentation, diagnostic workup, management, and prognosis of urinary bladder metastasis in breast cancer patients.
- Understanding these rare metastases aids in timely diagnosis and appropriate patient management.

