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Isolation and Identification of Extravascular Immune Cells of the Heart
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Isolation and Identification of Extravascular Immune Cells of the Heart

Published on: August 23, 2018

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Lymphoma Involving the Heart: A Case Report

Randa Tabbah1, Elissar Nohra2, Rachoin Rachoin3

  • 1Department of Cardiology, Holy Spirit University of Kaslik, Jounieh, Lebanon.

Frontiers in Cardiovascular Medicine
|April 8, 2020
PubMed

Insights

This case study details a rare primary cardiac lymphoma, a malignancy comprising less than 1% of heart tumors. Successful treatment involved R-CHOP chemotherapy and consideration for bone marrow transplant.

Area of Science:

  • Cardiology
  • Oncology
  • Hematology

Background:

  • Primary cardiac tumors are rare, accounting for less than 1% of all tumors, and often carry a poor prognosis.
  • Cardiac lymphomas are exceptionally rare malignancies within the heart.

Observation:

  • A 59-year-old patient presented with recurrent pleuropericarditis, low-grade fever, and night sweats.
  • Imaging revealed an infiltrating mass in the right atrioventricular groove, involving the right atrium and right ventricle.
  • Pathology confirmed the diagnosis of non-Hodgkin's lymphoma.

Findings:

  • The patient achieved initial remission with R-CHOP chemotherapy.
  • A recurrence was treated successfully with a second chemotherapy cycle.
  • The patient was considered a candidate for bone marrow transplant to prevent further relapses.

Implications:

  • Early diagnosis of primary cardiac lymphoma is crucial for improving long-term prognosis.
  • Aggressive chemotherapy regimens, like R-CHOP, can be effective in managing this rare condition.
  • Bone marrow transplantation may be considered for eligible patients to reduce relapse risk.

Keywords:
cardiac tumorscase reportlymphomapleuropericarditisprimaryright heart

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