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Lymphoma Involving the Heart: A Case Report
Randa Tabbah1, Elissar Nohra2, Rachoin Rachoin3
1Department of Cardiology, Holy Spirit University of Kaslik, Jounieh, Lebanon.
Frontiers in Cardiovascular Medicine
|April 8, 2020
Summary
This case study details a rare primary cardiac lymphoma, a malignancy comprising less than 1% of heart tumors. Successful treatment involved R-CHOP chemotherapy and consideration for bone marrow transplant.
Area of Science:
- Cardiology
- Oncology
- Hematology
Background:
- Primary cardiac tumors are rare, accounting for less than 1% of all tumors, and often carry a poor prognosis.
- Cardiac lymphomas are exceptionally rare malignancies within the heart.
Observation:
- A 59-year-old patient presented with recurrent pleuropericarditis, low-grade fever, and night sweats.
- Imaging revealed an infiltrating mass in the right atrioventricular groove, involving the right atrium and right ventricle.
- Pathology confirmed the diagnosis of non-Hodgkin's lymphoma.
Findings:
- The patient achieved initial remission with R-CHOP chemotherapy.
- A recurrence was treated successfully with a second chemotherapy cycle.
- The patient was considered a candidate for bone marrow transplant to prevent further relapses.
Implications:
- Early diagnosis of primary cardiac lymphoma is crucial for improving long-term prognosis.
- Aggressive chemotherapy regimens, like R-CHOP, can be effective in managing this rare condition.
- Bone marrow transplantation may be considered for eligible patients to reduce relapse risk.
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