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Updated: Dec 24, 2025

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
Voluntary Inhibitory Control of Chorea: A Case Series
Roberta Bonomo1,2,3, Anna Latorre1,4, Bettina Balint1,5
1Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology, University College London London United Kingdom.
Background:
Volitional control of involuntary movements has so far been considered a hallmark of tic disorders. However, modulation of involuntary movements can also be observed in other hyperkinesias.
Cases:
Here, we present 6 patients with chorea able to suppress their involuntary movements, on demand. In 3 of them, surface electromyography was used to quantify degree of suppression and confirmed a reduction of muscle activity up to 68%, during volitional control.
Conclusion:
This observation represents a first step toward a description of a new clinical feature in choreic syndromes and an opportunity to redefine the role of volitional inhibition in hyperkinetic movement disorders.
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