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Updated: Dec 24, 2025

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
Published on: September 20, 2024
Polymyalgia rheumatica and pulmonary adenocarcinoma: A case report and literature review
Sara Coelho1,2, Helena Magalhães1,2, Jorge Correia1
1Internal Medicine Department, Centro Hospitalar São João, E.P.E., Oporto, Portugal.
Abstract:
Polymyalgia rheumatica is an inflammatory rheumatologic condition that occurs frequently in the elderly. It has been, although infrequently, associated with malignancies, in a synchronous or closely time-related appearance. In such circumstances, polymyalgia rheumatica is considered to be a paraneoplastic syndrome and is often atypical in presentation with poor response to glucocorticoid treatment. We report the case of a 79-year-old woman in which the simultaneous diagnosis of polymyalgia rheumatica and lung adenocarcinoma was made. Rheumatologic symptoms responded partially to anti-inflammatory medication, with further response to lung cancer targeted chemotherapy.