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Updated: Dec 24, 2025

Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice
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NLRP3 inflammasome as a potential target to reduce epileptic-like activity: PS188

L Ribeiro-Rodrigues1, D M Rombo1, A M Sebastião1

  • 1Faculdade de Medicina, Universidade de Lisboa e Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Portugal.

Porto Biomedical Journal
|April 8, 2020
PubMed
Abstract

No abstract available in PubMed .

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Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
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