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Updated: Dec 24, 2025
Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
Uncontrolled donation after circulatory death improves access to kidney transplantation: A decision analysis
Rashikh A Choudhury1, Kas Prins1, Yoeli Dor1
1Department of Surgery, Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, USA.
Aim:
Uncontrolled donation after cardiac death (uDCD) remains an underutilized source of kidney allografts in the United States. The objective of this study was to estimate the impact of the implementation of a uDCD program on transplantation rates and long-term survival for patients with end-stage renal disease (ESRD) in the United States.
Methods:
A decision-analytic Markov state transition model was created using medical decision-making software (DATA 3.5; TreeAge Software, Inc) to estimate the impact of an uDCD program on transplantation rates and patient survival. Additionally, sensitivity analysis of uDCD donor pool increase was modeled. All model statistic parameters were extracted from the literature.
Results:
A uDCD program increased the rate of transplant at 10 years (37.8%, Accept uDCD group, vs 35.9%, Reject uDCD group). At 10 years, overall survival for Accept uDCD was 55.6% compared to 54.8% in the Reject uDCD.
Conclusions:
Uncontrolled DCD improves access to transplant for ESRD patients on the kidney transplant waitlist, thereby improving long-term survival.
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01:28Kidney Transplant I: Introduction
01:26Kidney Transplant II: Surgical Procedure