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Related Concept Videos

Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

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Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
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Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
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Echocardiographic reference ranges for normal left ventricular layer-specific strain: results from the EACVI NORRE

Toshimitsu Tsugu1,2, Adriana Postolache1, Raluca Dulgheru1

  • 1Department of Cardiology, GIGA Cardiovascular Sciences, University of Liège Hospital, Heart Valve Clinic, CHU Sart Tilman, CHU Sart Tilman, 4000 Liège, Belgium.

European Heart Journal. Cardiovascular Imaging
|April 8, 2020
PubMed
Summary

This study establishes normal reference ranges for left ventricular (LV) layer-specific strain using 2D echocardiography (2DE) in healthy adults. These findings provide crucial data for assessing cardiac function and diagnosing heart conditions.

Keywords:
2D echocardiographyadult echocardiographydeformation imagingreference values

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Assessing left ventricular (LV) function is critical in cardiovascular health.
  • Layer-specific strain analysis offers a more detailed evaluation of myocardial mechanics than traditional methods.
  • Establishing normal reference ranges is essential for accurate interpretation of echocardiographic measurements.

Purpose of the Study:

  • To determine the normal range for 2D echocardiographic (2DE) measurements of left ventricular (LV) layer-specific strain.
  • To provide reference values for epicardial, mid-myocardial, and endocardial strain in a large cohort of healthy individuals.
  • To investigate the influence of age and sex on LV layer-specific strain.

Main Methods:

  • Enrolled 287 healthy subjects (109 men, mean age 46±14 years) across 22 institutions.
  • Analyzed layer-specific strain from apical views using 2DE software.
  • Calculated normal ranges based on ±1.96 standard deviations from the mean.

Main Results:

  • Defined normal ranges for LV layer-specific strain: epicardial (-15.0% men, -15.6% women), mid-myocardial (-16.8% men, -17.7% women), and endocardial (-18.7% men, -19.9% women).
  • Observed age-related decreases in basal-epicardial and mid-myocardial strain in women, and correlations with age.
  • Found higher endocardial/epicardial strain ratios at the LV apex compared to middle and basal levels in both sexes.

Conclusions:

  • The EACVI NORRE study successfully established 2DE reference ranges for LV layer-specific strain.
  • These reference ranges are valuable for clinical assessment and research in cardiovascular imaging.
  • The findings highlight variations in strain by myocardial layer, age, and sex.