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A pH-responsive controlled release system using layered double hydroxide (LDH)-capped mesoporous silica nanoparticles
Qishan Zheng1, Yanli Hao, Peirong Ye
1Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, and Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China. lqguo@fzu.edu.cn.
Abstract:
A pH-responsive controlled release system is proposed using acid-decomposable layered double hydroxides (LDHs) as inorganic nanovalves by virtue of the electrostatic adsorption of LDH nanosheets on the surface of mesoporous silica nanoparticles (MSNs). Guest molecules (Ru(bpy)3Cl2 in this case) are loaded and encapsulated in a neutral environment. The dissolution of the LDH coatings in an acidic environment triggers the release of the guest molecules from the MSNs.
