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Updated: Dec 24, 2025
Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
Published on: November 14, 2018
A versatile ethanol-mediated polymerization of dopamine for efficient surface modification and the construction of
Qin Yue1, Minghong Wang, Zhenkun Sun
1Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State key laboratory of molecular engineering of polymers and Laboratory of Advanced Materials, Fudan University, Shanghai, 200433, P. R. China. yhdeng@fudan.edu.cn.
Abstract:
A versatile ethanol-mediated oxidative polymerization of dopamine is demonstrated for the effective surface modification of nanomaterials. The presence of ethanol is found to significantly slow down the polymerization rate of dopamine and make the surface modification of nanomaterials with polydopamine more controllable in comparison to the water-phase polymerization. Various nanomaterials with different morphologies and surface properties, including one-dimensional (1-D) CNTs and iron oxide nanorods, 2-D nanodiscs, silver nanocubes and magnetite particles, were successfully modified by a layer of PDA with a controllable thickness from 5 to 100 nm, giving rise to PDA-shelled nanocomposites with well-defined structures and excellent water dispersibility. As exemplified by the case of magnetite particles, the PDA coating can dramatically reduce the cytotoxicity of nanomaterials and enhance their biocompatibility. This method is facile and particularly suitable for the surface engineering of nanomaterials, and thus promising for designing various functional nanostructures for a broad range of applications, such as drug delivery, protein purification, enzyme immobilization, and chemo/biosensing.
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