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Updated: Dec 24, 2025

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
Prodrugs forming multifunctional supramolecular hydrogels for dual cancer drug delivery
Wei Ha1, Jing Yu, Xin-Yue Song
1Key Laboratory of Chemistry of Northwestern Plant Resources of CAS, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P. R. China. shiyp@licp.cas.cn.
Abstract:
Here we report a multifunctional supramolecular hydrogel based on host-guest inclusion for loading two different anticancer drugs with different controlled release profiles. The resulting hydrogels are characterized by possessing dual phase drug release behavior and producing a dose and cell type dependent synergetic cytotoxicity to cancer cells, which can be used for cancer combination therapy.

