Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Roles of astrocytic Connexin 43 gap junctional deficit in alpha-synucleinopathy and inflammation relevant to Parkinson's.

Experimental neurology·2026
Same author

Phase Homogeneity and Photothermal Stability in Fully Vacuum-Processed Perovskite Solar Cells.

ACS energy letters·2026
Same author

Brain-computer interfaces and neuroprosthetics in the next era of neurosurgery.

British journal of neurosurgery·2026
Same author

Fumarate dramatically enhances biocurrent output in Shewanella-based bioelectrochemical system.

Bioelectrochemistry (Amsterdam, Netherlands)·2026
Same author

ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

PloS one·2026
Same author

Time-Multiplexed Organic Electrochemical Transistor for Saliva-Based Rapid Detection of Viral Proteins.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same journal

Crosslinker-free PVA hydrogel incorporating a water-soluble Ir(III) photosensitizer for antibacterial photodynamic applications in wound healing.

Journal of materials chemistry. B·2026
Same journal

Precise microfluidic engineering of mRNA lipid nanoparticle-loaded polycaprolactone microcapsules for sustained delivery.

Journal of materials chemistry. B·2026
Same journal

Multifunctional polysulfone/strontium silicate composites with tunable properties through silane functionalization.

Journal of materials chemistry. B·2026
Same journal

Melanocortin 1 receptor-targeted peptide-functionalized liposomes for enhanced melanocyte-preferential drug delivery and anti-melanogenic efficacy.

Journal of materials chemistry. B·2026
Same journal

Recent progress in side-chain amino acid-based polymers: synthesis, self-assembly, and emerging biomedical applications.

Journal of materials chemistry. B·2026
Same journal

Bioinspired electrospun nanofibrous dressings loaded with Mentha-derived exosome-like vesicles for antibacterial and immunomodulatory burn healing.

Journal of materials chemistry. B·2026
See all related articles

Related Experiment Video

Updated: Dec 24, 2025

A Simple and Scalable Fabrication Method for Organic Electronic Devices on Textiles
06:21

A Simple and Scalable Fabrication Method for Organic Electronic Devices on Textiles

Published on: March 13, 2017

10.8K

A facile biofunctionalisation route for solution processable conducting polymer devices.

Xenofon Strakosas1, Michele Sessolo, Adel Hama

  • 1Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC, 13541, France. owens@emse.fr.

Journal of Materials Chemistry. B
|April 9, 2020
PubMed
Summary
This summary is machine-generated.

This study presents a new method for covalently attaching biomolecules to conducting polymer films. This versatile technique enhances biosensor stability and function without compromising electronic properties.

More Related Videos

Reactive Vapor Deposition of Conjugated Polymer Films on Arbitrary Substrates
07:32

Reactive Vapor Deposition of Conjugated Polymer Films on Arbitrary Substrates

Published on: January 17, 2018

36.1K
Morphology Control for Fully Printable Organic–Inorganic Bulk-heterojunction Solar Cells Based on a Ti-alkoxide and Semiconducting Polymer
08:29

Morphology Control for Fully Printable Organic–Inorganic Bulk-heterojunction Solar Cells Based on a Ti-alkoxide and Semiconducting Polymer

Published on: January 10, 2017

9.3K

Related Experiment Videos

Last Updated: Dec 24, 2025

A Simple and Scalable Fabrication Method for Organic Electronic Devices on Textiles
06:21

A Simple and Scalable Fabrication Method for Organic Electronic Devices on Textiles

Published on: March 13, 2017

10.8K
Reactive Vapor Deposition of Conjugated Polymer Films on Arbitrary Substrates
07:32

Reactive Vapor Deposition of Conjugated Polymer Films on Arbitrary Substrates

Published on: January 17, 2018

36.1K
Morphology Control for Fully Printable Organic–Inorganic Bulk-heterojunction Solar Cells Based on a Ti-alkoxide and Semiconducting Polymer
08:29

Morphology Control for Fully Printable Organic–Inorganic Bulk-heterojunction Solar Cells Based on a Ti-alkoxide and Semiconducting Polymer

Published on: January 10, 2017

9.3K

Area of Science:

  • Materials Science
  • Bioelectronics
  • Polymer Chemistry

Background:

  • Biomedical device and biosensor functionality relies on effective biorecognition element immobilization.
  • Covalent immobilization offers superior device longevity and controlled functionalization compared to passive methods.
  • Organic bioelectronics utilizes conducting polymers for signal transduction, but solution-processed film functionalization remains underdeveloped.

Purpose of the Study:

  • To develop a versatile covalent biofunctionalization technique for solution-processable conducting polymers.
  • To enable low-cost, high-throughput fabrication of functionalized bioelectronic devices.
  • To investigate the impact of biofunctionalization on the properties of conducting polymer films.

Main Methods:

  • Incorporation of poly(vinyl alcohol) (PVA) into poly(3,4-ethylenedioxythiophene) doped with poly(styrenesulfonate) (PEDOT:PSS) solutions.
  • Subsequent silanization of PEDOT:PSS:PVA films using a silane reagent for covalent linkage.
  • Homogenous and large-scale immobilization of polypeptides and proteins onto the functionalized films.

Main Results:

  • Successful covalent attachment of biological moieties to PEDOT:PSS films via PVA.
  • Demonstration of homogenous and large-scale biofunctionalization with polypeptides and proteins.
  • Preservation of biological functionalities of immobilized proteins.
  • No adverse effects on the electronic or ionic transport properties of the PEDOT:PSS films.

Conclusions:

  • A versatile and effective method for covalent biofunctionalization of solution-processable PEDOT:PSS films has been established.
  • The developed technique allows for stable immobilization of biomolecules, enhancing biosensor capabilities.
  • The method is compatible with large-scale fabrication and preserves the intrinsic properties of the conducting polymer.