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Updated: Aug 24, 2026

Combining QD-FRET and Microfluidics to Monitor DNA Nanocomplex Self-Assembly in Real-Time
Published on: August 26, 2009
Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy
Jeong Hoon Byeon1, Young-Woo Kim
1Department of Chemistry, Purdue University, Indiana 47907, USA. jbyeon@purdue.edu.
Abstract:
The gene transfection efficiency of Au@PDMS-PLL soft nanocomposites was higher than those of SiO2-PLL and PEI; and moreover, the nanocomposites did not show significant cell cytotoxicity in in vitro measurements. The soft nanocomposites were also sensitive during photothermal therapy with infrared light, which produced a cytotoxic effect on the targeted HeLa cells.
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