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Updated: Dec 24, 2025
Specific Labeling of Mitochondrial Nucleoids for Time-lapse Structured Illumination Microscopy
Published on: June 4, 2020
High-bright fluorescent carbon dots and their application in selective nucleoli staining
Weiqian Kong1, Ruihua Liu, Hao Li
1Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Jiangsu 215123, China. yangl@suda.edu.cn zhkang@suda.edu.cn.
Abstract:
Fluorescent carbon dots (FCDs) were synthesized by refluxing polyethylene glycol, which can emit bright and different fluorescent colours under various wavelengths as well as show stable fluorescence properties with different ionic strength, temperature and time. These FCDs exhibit good biocompatibility and very low toxicity for HeLa cells. Notably, these FCDs, as an efficient live cell fluorescence imaging probe, can selectively stain nucleoli, and the effect is similar to some commercially available dyes (such as Hoechst).
