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Updated: Dec 24, 2025

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Microfibrous borate bioactive glass dressing sequesters bone-bound bisphosphonate in the presence of simulated body
Chandrani Pramanik1, Tianda Wang, Sushanta Ghoshal
1School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA. satish.kumar@gatech.edu.
Abstract:
Ion exchange occurs between borate bioactive glass and simulated body fluid. Borate bioactive glass dressings may be used for managing bisphosphonate-related osteonecrosis of the jaw through the formation of a complex incorporating leached calcium and borate ions and sequestered bone-bound bisphosphonates.
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